Study of Synthesis of 3'-Deoxy-3'-[18F]fluorothymidine – Prospective Radiopharmaceutical in Positron Emission Tomography

Autoři

  • L. Procházka Nuclear Physics Institute, Academy of Sciences of the Czech Republic, Řež near Prague
  • M. Kropáček Nuclear Physics Institute, Academy of Sciences of the Czech Republic, Řež near Prague
  • M. Mirzajevová Nuclear Physics Institute, Academy of Sciences of the Czech Republic, Řež near Prague
  • J. Zimová Nuclear Physics Institute, Academy of Sciences of the Czech Republic, Řež near Prague
  • M. Försterová Nuclear Physics Institute, Academy of Sciences of the Czech Republic, Řež near Prague
  • H. Švecová Nuclear Physics Institute, Academy of Sciences of the Czech Republic, Řež near Prague
  • F. Melichar Nuclear Physics Institute, Academy of Sciences of the Czech Republic, Řež near Prague

Abstrakt

18F-Labelled compounds as active substances of radiopharmaceuticals are used for imaging in positron emission tomography (PET) in nuclear medicine. The radiosynthesis of PET radiopharmaceuticals is based on nucleophilic substitution with F? in a precursor. The synthesis is demonstrated on 3'-deoxy-3'-[18F]fluorothymidine.

Stahování

Publikováno

15.12.2008

Jak citovat

Procházka, L., Kropáček, M., Mirzajevová, M., Zimová, J., Försterová, M., Švecová, H., & Melichar, F. (2008). Study of Synthesis of 3’-Deoxy-3’-[18F]fluorothymidine – Prospective Radiopharmaceutical in Positron Emission Tomography. Chemické Listy, 102(11). Získáno z http://blog.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/1601

Číslo

Vol 102 No 11 (2008)

Sekce

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