Trinderova reakce v klinické biochemii – přínosy a limity

Abstrakt

This article reviews the Trinder chromogenic reaction and describes its discovery, further development, current state and use in practice. It has been known for nearly half a century as a universal and analytically specific chromogenic method that is abundantly used in clinical biochemistry tests. The article provides information on the benefits and shortcomings of the Trinder reaction in comparison to alternative methods. It also reviews substances interfering in this reaction. This may be particularly helpful for a biochemical analyst or a physician in determination the cause of discrepant laboratory results, and thus prevent an application of improper patient treatment.