HPLC Determination of Norepinephrine in Pharmaceuticals
Keywords:
HPLC, ion-exchange chromatography, noradrenaline, drugsAbstract
The aim of the work was to develop a new chromatographic method for the determination of norepinephrine in intravenous infusions. The new method is based on separation of norepinephrine and the internal standard paracetamol on a strongly acid cation exchanger. The validation parameters of the method were satisfactory. The method is applicable for the above purpose in routine analysis.