Determination of Mercury Species in Human Blood Using Combined GC and MS with Inductively Coupled Plasma

Authors

  • Rastislav Serbin Department of Environmental Medicine, Slovak University of Medicine, Bratislava, Slovak Republic
  • Iveta Uhnáková Department of Environmental Medicine, Slovak University of Medicine, Bratislava, Slovak Republic
  • Zuzana Hušeková Department of Environmental Medicine, Slovak University of Medicine, Bratislava, Slovak Republic
  • Monika Ursínyová Department of Environmental Medicine, Slovak University of Medicine, Bratislava, Slovak Republic

Keywords:

methylmercury, mercury, blood, speciation, GC-ICP-MS

Abstract

A simple method for methylmercury (MeHg+) determination in human venous blood is described using GC-ICP-MS. The blood sample preparation consists in the extraction with a mixture of 6M HCl and NaCl, pH adjustment, derivatization of mercury species using NaBPh4 with simultaneous extraction of products into hexane. The detection limits for MeHg+ were 86 ppt (as Hg) in the optimized method. The sample volume for repeated measurements was 150 mL. The total Hg level in blood was determined by AAS using the amalgamation technique.

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Published

2011-11-15

How to Cite

Serbin, R., Uhnáková, I., Hušeková, Z., & Ursínyová, M. (2011). Determination of Mercury Species in Human Blood Using Combined GC and MS with Inductively Coupled Plasma. Chemické Listy, 105(11), 890–895. Retrieved from http://blog.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/1035

Issue

Vol. 105 No. 11 (2011)

Section

Articles

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