Biological Sensing Elements for the Detection of N-acyl Homoserine Lactones

Authors

  • M. Paldrychová Department of Biotechnology, University of Chemistry and Technology, Prague
  • A. Čejková Department of Biotechnology, University of Chemistry and Technology, Prague
  • J. Masák Department of Biotechnology, University of Chemistry and Technology, Prague

Keywords:

quorum sensing, signal molecules, N-acyl-homoserine lactone, biological sensing element, Agrobacterium tumefaciens

Abstract

Many Gram-negative bacteria use N-acyl-homoserine lactones (N-acyl-HSL) as quorum sensing signal molecules. N-acyl-HSL are the subject of investigation by many research groups. Simple methods have been designed to detect N‑acyl-HSL using bacterial strains that doesn't produce its own signal molecules, but the reporter gene is expressed when exogenous N-acyl-HSL are present. This article reviews and discusses the most common and most currently obtainable systems using bacteria such as Agrobacterium tumefaciens, Chromobacterium violaceum, Escherichia coli or Vibrio fischeri. These biological sensing elements can be used to detect and study a wide range of N-acyl-HSL and related molecules interfering with quorum sensing systems.

Published

2019-08-15

How to Cite

Paldrychová, M., Čejková, A., & Masák, J. (2019). Biological Sensing Elements for the Detection of N-acyl Homoserine Lactones. Chemické Listy, 113(8), 485–490. Retrieved from http://blog.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/3432

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